Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.42 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.42 |
| ▸ | PIM1 | P11309 | 2/20 | 0.42 |
| ▸ | DHFR | P00374 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | CDK8 | P49336 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065139 | 0.74 | IMPDH2 (0.48) | CHEK1 | |
| SCHEMBL13312259 | 0.74 | NPC1 (0.47) | NPC1RAB9AATMADORA2AADORA1 | |
| SCHEMBL3485241 | 0.73 | PARP1 (0.47) | HSD17B10ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL2495533 | 0.71 | ALDH1A1 (0.53) | NPC1RAB9APIM1CHEK1HSD17B10 | |
| SCHEMBL5064948 | 0.71 | ADORA2A (0.40) | ADORA2AADORA1PIM1CHEK1HSD17B10 | |
| SCHEMBL23931336 | 0.69 | KDM4E (0.54) | NPC1RAB9AATMADORA2AADORA1 | |
| SCHEMBL30124898 | 0.69 | STK4 (0.61) | NPC1RAB9AATMADORA2AADORA1 | |
| SCHEMBL20360672 | 0.68 | TDO2 (0.52) | NPC1RAB9AATMADORA2AADORA1 | |
| SCHEMBL4245392 | 0.68 | KDM4E (0.55) | NPC1RAB9AADORA2AHSD17B10CYP1A2 | |
| SCHEMBL14350065 | 0.68 | NPC1 (0.53) | NPC1RAB9AATMADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080261823-A1 | Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-10-23 | — | — | US | claimed |
| WO-2006076102-A2 | FLUORESCENT NUCLEOSIDE ANALOGS THAT MIMIC NATURALLY OCCURRING NUCLEOSIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | claimed |
| US-20080261823-A1 | Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2008-10-23 | — | — | US | disclosed |
| WO-2006076102-A2 | FLUORESCENT NUCLEOSIDE ANALOGS THAT MIMIC NATURALLY OCCURRING NUCLEOSIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2006-07-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080261823-A1 | Fluorescent Nucleoside Analogs That Mimic Naturally Occurring Nucleosides | NSUN2, NSUN3, NCL | NPC1 1433/4885RAB9A 4274/4885ATM 3937/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.