SCHEMBL2495893

SCHEMBL2495893

CCCCCB(CCCCC)CCCCC.[LiH]

nearest known ligand 0.47

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.47
THRB P10828 1/20 0.47
LMNA P02545 3/20 0.40
ANPEP P15144 1/20 0.40
SLC22A1 O15245 3/20 0.37
SLC22A2 O15244 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
DNM1 Q05193 5/20 0.35
ALDH1A1 P00352 3/20 0.35
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11524980 0.96 TSHR (0.50) TSHRTHRBLMNAANPEPSLC22A1
SCHEMBL88650 0.96 TSHR (0.50) TSHRTHRBLMNAANPEPSLC22A1
SCHEMBL488468 0.93 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL487870 0.93 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL2078883 0.93 TSHR (0.47) TSHRTHRBLMNAANPEPSLC22A1
SCHEMBL556924 0.93 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL11331724 0.93 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL8845927 0.93 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL332105 0.93 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL29385729 0.93 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 78 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118344599-A Nano sheet manganese-based metal organic framework material, preparation method thereof and photoelectric device 邯郸学院 2024-07-16 CN claimed
CN-117954722-A Method for synchronously realizing repair and surface coating of waste lithium ion battery positive electrode material regeneration 中南大学 2024-04-30 CN claimed
CN-116917341-A Sugar chain and method for producing pharmaceutical product containing sugar chain 第一三共株式会社 2023-10-20 CN claimed
EP-1810967-B1 Processes and intermediates for the preparations of prostaglandins CHIROGATE INT INC (TW) 2014-07-30 EP claimed
US-20080039637-A1 Processes and intermediates for the preparations of prostaglandins CHIROGATE INTERNATIONAL INC. 2008-02-14 US claimed
EP-1810967-A1 Processes and intermediates for the preparations of prostaglandins Chirogate International Inc. (TW) 2007-07-25 EP claimed
US-20070167641-A1 Processes and intermediates for the preparations of prostaglandins CHIROGATE INTERNATIONAL INC. 2007-07-19 US claimed
WO-1995027715-A2 METHOD OF MANUFACTURE OF (-)GALANTHAMINE IN HIGH YIELD AND PURITY SUBSTANTIALLY FREE OF EPIGALANTHAMINE CIBA-GEIGY CORPORATION (US) 1995-10-19 WO claimed
US-5428159-A Resolution of racemic mixture; reduction CIBA-GEIGY CORPORATION (US) 1995-06-27 US claimed
US-12497375-B2 Processes and intermediates for the preparations of benzoprostacyclin analogues and benzoprostacyclin analogues prepared therefrom CHIROGATE INTERNATIONAL INC. (TW) 2025-12-16 US disclosed
US-12497374-B2 Processes and intermediates for the preparations of benzoprostacyclin analogues and benzoprostacyclin analogues prepared therefrom CHIROGATE INTERNATIONAL INC. (TW) 2025-12-16 US disclosed
US-20250304519-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES CHIROGATE INTERNATIONAL INC. (TW) 2025-10-02 US disclosed
US-12428361-B2 Processes and intermediates for the preparation of carbaprostacyclin analogues CHIROGATE INTERNATIONAL INC. (TW) 2025-09-30 US disclosed
EP-4273131-B1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES CHIROGATE INT INC (TW) 2025-07-02 EP disclosed
EP-1549350-A1 PHARMACEUTICALLY ACTIVE OLIGOSACCHARIDE CONJUGATES Fresenius Kabi Deutschland GmbH (DE) 2005-07-06 EP disclosed
WO-2004032971-A1 PHARMACEUTICALLY ACTIVE OLIGOSACCHARIDE CONJUGATES FRESENIUS KABI DEUTSCHLAND GMBH (DE) 2004-04-22 WO disclosed
US-5856590-A HYDROGENATING 4-T-BUTYLCYCLOHEXANONE BY USING A SPECIFIC RUTHENIUM-PHOSPHINE COMPLEX AS A CATALYST IN THE PRESENCE OF A BASE TAKASAGO INTERNATIONAL CORPORATION (JP) 1999-01-05 US disclosed
EP-0240175-B1 INOSOSE DERIVATIVES AND PRODUCTION THEREOF Takeda Chemical Industries, Ltd. (JP) 1991-10-16 EP disclosed
US-4824943-A Inosose derivatives and production thereof TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1989-04-25 US disclosed
EP-0240175-A1 Inosose derivatives and production thereof Takeda Chemical Industries, Ltd. (JP) 1987-10-07 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12428361-B2 Processes and intermediates for the preparation of carbaprostacyclin analogues PTGIS, PTGIR, PTGES TSHR 4673/4885THRB 4728/4885LMNA 500/4885
US-20070167641-A1 Processes and intermediates for the preparations of prostaglandins PTGES, PTGER1, PTGIS TSHR 2650/4885THRB 3669/4885LMNA 1678/4885
US-20080039637-A1 Processes and intermediates for the preparations of prostaglandins PTGES, PTGER1, PTGIS TSHR 2650/4885THRB 3669/4885LMNA 1678/4885
US-12497374-B2 Processes and intermediates for the preparations of benzoprostacyclin analogues and benzoprostacyclin analogues prepared therefrom PTGIS, PTGER1, PTGIR TSHR 2552/4885THRB 3405/4885LMNA 346/4885
US-20250304519-A1 PROCESSES AND INTERMEDIATES FOR THE PREPARATION OF CARBAPROSTACYCLIN ANALOGUES PTGIS, PTGIR, PTGES TSHR 4673/4885THRB 4728/4885LMNA 500/4885
US-12497375-B2 Processes and intermediates for the preparations of benzoprostacyclin analogues and benzoprostacyclin analogues prepared therefrom PTGIS, PTGIR, PTGES TSHR 3431/4885THRB 4431/4885LMNA 1214/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.