SCHEMBL88650

SCHEMBL88650

CCCCCB(CCCCC)CCCCC

nearest known ligand 0.50

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.50
THRB P10828 1/20 0.50
LMNA P02545 3/20 0.43
ANPEP P15144 1/20 0.42
SLC22A1 O15245 3/20 0.39
SLC22A2 O15244 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
DNM1 Q05193 5/20 0.37
ALDH1A1 P00352 3/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
HSD17B10 Q99714 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11524980 1.00 TSHR (0.50) TSHRTHRBLMNAANPEPSLC22A1
SCHEMBL556924 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL2495893 0.96 TSHR (0.47) TSHRTHRBLMNAANPEPSLC22A1
SCHEMBL2078883 0.96 TSHR (0.47) TSHRTHRBLMNAANPEPSLC22A1
SCHEMBL11331724 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL488468 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL487870 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL8845927 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL332105 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1
SCHEMBL29385729 0.96 TSHR (0.57) TSHRTHRBLMNASLC22A1DNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1624 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116396419-A Alpha-olefin/maleic anhydride alternating copolymer and preparation method thereof 中国科学院长春应用化学研究所 2023-07-07 CN claimed
CN-116284529-A Preparation method of isobutene or derivative-maleic anhydride alternating copolymer 中国科学院长春应用化学研究所 2023-06-23 CN claimed
CN-107995905-B Highly reactive metal hydrides, method for the production thereof and use thereof 雅宝德国有限责任公司 2021-03-30 CN claimed
US-9050590-B2 Catalytic composition and process for oligomerization of olefins using said catalytic composition IFP Energies Nouvelles (FR) 2015-06-09 US claimed
EP-2572783-B1 Method of separating pentene-2 from a C5 cut containing pentene-2 and pentene-1 by selective oligomerisation of the pentene-1 IFP Energies Nouvelles (FR) 2014-11-12 EP claimed
EP-2572782-B1 Method for separating butene-2 from a C4 cut containing butene-2 and butene-1 by selective oligomerisation of the butene-1 IFP Energies Nouvelles (FR) 2014-10-22 EP claimed
US-20130211168-A1 CATALYTIC COMPOSITION AND PROCESS FOR OLIGOMERIZATION OF OLEFINS USING SAID CATALYTIC COMPOSITION IFP Energies Nouvelles (FR) 2013-08-15 US claimed
EP-2572783-A1 Method of separating pentene-2 from a C5 cut containing pentene-2 and pentene-1 by selective oligomerisation of the pentene-1 IFP Energies Nouvelles (FR) 2013-03-27 EP claimed
EP-2572782-A1 ***Method for separating butene-2 from a C4 cut containing butene-2 and butene-1 by selective oligomerisation of the butene-1 IFP Energies Nouvelles (FR) 2013-03-27 EP claimed
US-20130072733-A1 METHOD OF SEPARATING PENTENE-2 FROM A C5 CUT CONTAINING PENTENE-2 AND PENTENE-1 BY SELECTIVE OLIGOMERIZATION OF PENTENE-1 IFP Energies Nouvelles (FR) 2013-03-21 US claimed
US-6368999-B1 METALLOCENE POLYEMRIZATION CATALYST, ACTIVATOR, AND A SUPPORT THAT HAS BEEN FLUORIDED USING A FLUORIDE CONTAINING COMPOUND, REACTIVE FUNCTIONALITIES OF THE SUPPORT ARE REDUCED AND/OR DEACTIVATED EXXON MOBIL CHEMICAL PATENTS INC. 2002-04-09 US claimed
WO-2002016480-A2 POLYPROPYLENE FILMS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2002-02-28 WO claimed
CN-1303386-A Synthesis method of alkali metal substituted borohydride reagent MINE SAFETY APPLIANCES CO (US) 2001-07-11 CN claimed
EP-0910593-B1 ELASTOMERS AND PROCESS FOR THEIR MANUFACTURE DOW CHEMICAL CO (US) 2001-04-18 EP claimed
US-6150560-A Recovery of tris(aryl)borane from their tetrahydrofuran complexes ALBEMARLE CORPORATION (US) 2000-11-21 US claimed
WO-2000064907-A1 RECOVERY OF TRIS(ARYL)BORANE FROM THEIR TETRAHYDROFURAN COMPLEXES ALBEMARLE CORPORATION (US) 2000-11-02 WO claimed
WO-1995027715-A2 METHOD OF MANUFACTURE OF (-)GALANTHAMINE IN HIGH YIELD AND PURITY SUBSTANTIALLY FREE OF EPIGALANTHAMINE CIBA-GEIGY CORPORATION (US) 1995-10-19 WO claimed
EP-0266220-B1 CURABLE COMPOSITION MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1993-01-07 EP claimed
US-4985516-A MONOACRYLATE, POLYACRYLATE, ACID ACRYLATE MONOMER, TRIALKYLBORON OR ITS OXIDE MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-01-15 US claimed
EP-0266220-A2 Curable composition MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1988-05-04 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130211168-A1 CATALYTIC COMPOSITION AND PROCESS FOR OLIGOMERIZATION OF OLEFINS USING SAID CATALYTIC COMPOSITION AOC2, AOC3, ALOX15 TSHR 3525/4885THRB 4087/4885LMNA 4405/4885
US-20130072733-A1 METHOD OF SEPARATING PENTENE-2 FROM A C5 CUT CONTAINING PENTENE-2 AND PENTENE-1 BY SELECTIVE OLIGOMERIZATION OF PENTENE-1 C5, C9, OXER1 TSHR 4404/4885THRB 3513/4885LMNA 1229/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.