Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 14/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23080309 | 0.88 | ACHE (0.37) | RAPGEF4ALDH1A1LMNA | |
| SCHEMBL317299 | 0.75 | RAPGEF4 (0.50) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL13547715 | 0.74 | RAPGEF4 (0.39) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL22318112 | 0.74 | RAPGEF4 (0.39) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL14016309 | 0.70 | ALDH1A1 (0.52) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL339301 | 0.69 | RAPGEF4 (0.45) | RAPGEF4KDM4EALDH1A1LMNAGAA | |
| SCHEMBL20682673 | 0.69 | ALDH1A1 (0.37) | RAPGEF4ALDH1A1 | |
| SCHEMBL8354030 | 0.69 | ACHE (0.40) | RAPGEF4ALDH1A1 | |
| SCHEMBL19186545 | 0.69 | ALDH1A1 (0.30) | ALDH1A1 | |
| SCHEMBL13083360 | 0.69 | ACHE (0.48) | RAPGEF4KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230024370-A1 | LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2023-01-26 | — | — | US | disclosed |