Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PARP1 | P09874 | 4/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.32 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7727344 | 0.81 | TAAR1 (0.40) | PARP1PAK1PDPK1CA12ALOX15 | |
| SCHEMBL22559041 | 0.78 | CYP1A2 (0.39) | PARP1PAK1PDPK1CA12ALOX15 | |
| SCHEMBL14477036 | 0.75 | TSHR (0.42) | PARP1PAK1PDPK1CA12ALOX15 | |
| SCHEMBL2497541 | 0.74 | CXCL8 (0.39) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| SCHEMBL2496022 | 0.74 | PARP1 (0.41) | PARP1SMN1; SMN2 | |
| SCHEMBL3866726 | 0.73 | PARP1 (0.37) | PARP1PAK1PDPK1CA12ALOX15 | |
| SCHEMBL2820813 | 0.73 | CXCL8 (0.40) | PARP1PAK1PDPK1CA12ALOX15 | |
| SCHEMBL10536 | 0.70 | DYRK1A (0.38) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| SCHEMBL2498957 | 0.68 | MEN1 (0.39) | PARP1PDPK1CA12ALOX15SMN1; SMN2 | |
| SCHEMBL8303802 | 0.68 | ATM (0.38) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2373628-A1 | NOVEL COMPOUNDS | Glaxo Group Limited (GB) | 2011-10-12 | — | — | EP | disclosed |
| WO-2010070021-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2010-06-24 | — | — | WO | disclosed |