Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAV | P06756 | 19/20 | 0.42 |
| ▸ | ITGB6 | P18564 | 18/20 | 0.42 |
| ▸ | ITGA5 | P08648 | 16/20 | 0.42 |
| ▸ | MPO | P05164 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22645202 | 0.90 | ITGAV (0.40) | ITGAVITGB6ITGA5 | |
| SCHEMBL21328984 | 0.85 | ITGAV (0.43) | ITGAVITGB6ITGA5ITGB3 | |
| SCHEMBL21328983 | 0.85 | ITGAV (0.43) | ITGAVITGB6ITGA5ITGB3 | |
| SCHEMBL25636389 | 0.81 | ITGAV (0.39) | ITGAVITGB6ITGA5 | |
| SCHEMBL20021726 | 0.79 | PPARG (0.42) | ITGAVITGB6ITGA5MPOITGB3 | |
| SCHEMBL24908842 | 0.78 | ITGAV (0.62) | ITGAVITGB6ITGA5ITGB3ITGB5 | |
| SCHEMBL21328931 | 0.78 | ALDH1A1 (0.35) | ITGAVITGB6MPO | |
| SCHEMBL21317504 | 0.77 | MPO (0.39) | ITGAVITGB6MPO | |
| SCHEMBL26462061 | 0.77 | MPO (0.38) | ITGAVITGB6MPO | |
| SCHEMBL21340267 | 0.76 | MPO (0.35) | ITGAVITGB6ITGA5MPOITGB3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230271960-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | PLIANT THERAPEUTICS INC (US) | 2023-08-31 | — | — | US | disclosed |
| US-11560376-B2 | Amino acid compounds and methods of use | PLIANT THERAPEUTICS, INC. (US) | 2023-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271960-A1 | AMINO ACID COMPOUNDS AND METHODS OF USE | ITGB6, ITGA6, ITGA5 | ITGAV 4/4885ITGB6 1/4885ITGA5 3/4885 |
| US-11560376-B2 | Amino acid compounds and methods of use | ITGB6, ITGA6, ITGA5 | ITGAV 4/4885ITGB6 1/4885ITGA5 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.