SCHEMBL2496360

SCHEMBL2496360

CCCc1cc(OC)c(OC)cc1OC

nearest known ligand 0.73

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 2/20 0.67
TAAR1 Q96RJ0 4/20 0.55
CYP19A1 P11511 1/20 0.53
HTR2A P28223 6/20 0.50
CYP3A4 P08684 1/20 0.50
HTR2C P28335 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30136435 1.00 HMGCR (0.67) HMGCRTAAR1CYP19A1HTR2ACYP3A4
SCHEMBL28748249 1.00 HMGCR (0.67) HMGCRTAAR1CYP19A1HTR2ACYP3A4
SCHEMBL23222349 0.90 HMGCR (0.72) HMGCRTAAR1CYP19A1HTR2ACYP3A4
SCHEMBL12892627 0.88 TAAR1 (0.70) HMGCRTAAR1HTR2ACYP3A4HTR2C
SCHEMBL29376427 0.85 TAAR1 (0.78) TAAR1HTR2AHTR2C
SCHEMBL23424386 0.85 TAAR1 (0.69) HMGCRTAAR1HTR2AHTR2C
SCHEMBL2562751 0.85 TAAR1 (0.78) TAAR1HTR2AHTR2C
SCHEMBL12250880 0.84 HMGCR (0.64) HMGCRTAAR1HTR2ACYP3A4
Butyric Acid SCHEMBL28877004 0.84 HMGCR (0.59) HMGCRTAAR1CYP19A1CYP3A4
SCHEMBL11793593 0.83 HMGCR (0.81) HMGCRTAAR1HTR2AHTR2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 123 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6969778-B2 DDQ mediated one step dimerization of β-asarone or β-asarone rich Acorus calamus oil in the formation of novel neolignan COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2005-11-29 US claimed
WO-2003082786-A1 A PROCESS FOR THE PREPARATION OF PHARMACOLOGICALLY ACTIVE ALPHA-ASARONE FROM TOXIC BETA-ASARONE RICH ACORUS CALAMUS OIL COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) 2003-10-09 WO claimed
US-6590127-B1 Formation of alpha-asarone, isoacoramone and 2,4,5-trimethoxycinnamaldehyde in one step process via 2,3-dichloro-5,6-dicyano-1,4-benzoquinone assisted dehydrogenation/oxidation of 2,4,5-trimethoxyphenylpropane COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) 2003-07-08 US claimed
US-20030113275-A1 Process for the preparation of 1-Propyl-2, 4, 5- trimethoxybenzene from toxic beta-asarone of Acorus calamus or from crude calamus oil containing beta-asarone COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2003-06-19 US claimed
US-20020035299-A1 Process for the preparation of 1-Propyl-2, 4, 5-trimethoxybenzene from toxic beta-asarone of acorus calamus or from crude calamus oil containing beta-asarone COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH 2002-03-21 US claimed
EP-4011921-B1 RUBBER WITH BACKBONE AND END-GROUP FUNCTIONALIZATION AND ITS METHOD OF MANUFACTURING AND USE IN A TIRE G 3 CHICKADEE PURCHASER LLC 1485 E ARCHWOOD AVENUE (US) 2026-02-04 EP disclosed
EP-4446001-A1 IMPROVEMENTS IN OR RELATING TO ORGANIC COMPOUNDS Givaudan SA (CH) 2024-10-16 EP disclosed
CN-114621375-B Rubber with backbone and end-group functionalization 固特异轮胎和橡胶公司 2024-06-18 CN disclosed
US-20240173230-A1 FRAGRANCE COMPOSITION GIVAUDAN SA (CH) 2024-05-30 US disclosed
EP-3310893-B2 IMPROVEMENTS IN OR RELATING TO ENCAPSULATED PERFUME COMPOSITIONS GIVAUDAN SA (CH) 2024-02-28 EP disclosed
US-11912798-B2 Rubber with backbone and end-group functionalization THE GOODYEAR TIRE & RUBBER COMPANY (US) 2024-02-27 US disclosed
US-20230312798-A1 FUNCTIONALIZED HYDROGENATED POLYMERS MIZUHO BANK, LTD., AS ADMINISTRATIVE AGENT 2023-10-05 US disclosed
EP-0438967-B1 Segmented elastomer GOODYEAR TIRE & RUBBER (US) 1996-05-01 EP disclosed
US-5239009-A Butadiene, isoprene, styrene random polymer, wear resistance, good traction tire treads THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-08-24 US disclosed
US-5202387-A Modified styrene-butadiene copolymer; catalytic polymerization using living-catalyst THE GOODYEAR TIRE & RUBBER COMPANY (US) 1993-04-13 US disclosed
US-5100965-A Process for synthesizing high trans polymers THE GOODYEAR TIRE & RUBBER COMPANY (US) 1992-03-31 US disclosed
US-5070148-A SEGMENTED ELASTOMER THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-12-03 US disclosed
EP-0438967-A1 Segmented elastomer THE GOODYEAR TIRE & RUBBER COMPANY (US) 1991-07-31 EP disclosed
EP-0258167-A2 Modifier for lithium catalysts THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-03-02 EP disclosed
US-4696986-A 1,2,3- OR 1,2,4-TRIALKOXYBENZENE MODIFIERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1987-09-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020035299-A1 Process for the preparation of 1-Propyl-2, 4, 5-trimethoxybenzene from toxic beta-asarone of acorus calamus or from crude calamus oil containing beta-asarone ADRA2B, CYP1B1, ADRB1 HMGCR 365/4885TAAR1 135/4885CYP19A1 71/4885
US-20240173230-A1 FRAGRANCE COMPOSITION FABP2, FABP5, FAAH2 HMGCR 1696/4885TAAR1 1192/4885CYP19A1 167/4885
US-20030113275-A1 Process for the preparation of 1-Propyl-2, 4, 5- trimethoxybenzene from toxic beta-asarone of Acorus calamus or from crude calamus oil containing beta-asarone ADRA2B, CYP1B1, ADRB1 HMGCR 348/4885TAAR1 140/4885CYP19A1 72/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.