Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFKB1 | P19838 | 2/20 | 0.41 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.41 |
| ▸ | RELA | Q04206 | 2/20 | 0.41 |
| ▸ | CTSS | P25774 | 2/20 | 0.40 |
| ▸ | CTSK | P43235 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24754820 | 1.00 | NFKB1 (0.41) | NFKB1NFKB2RELACTSSCTSK | |
| SCHEMBL19606034 | 1.00 | NFKB1 (0.41) | NFKB1NFKB2RELACTSSCTSK | |
| SCHEMBL24584247 | 1.00 | NFKB1 (0.41) | NFKB1NFKB2RELACTSSCTSK | |
| SCHEMBL23782042 | 0.93 | NFKB1 (0.43) | NFKB1NFKB2RELA | |
| SCHEMBL14838051 | 0.93 | NFKB1 (0.43) | NFKB1NFKB2RELA | |
| SCHEMBL6530320 | 0.93 | NFKB1 (0.43) | NFKB1NFKB2RELA | |
| SCHEMBL4954867 | 0.93 | NFKB1 (0.43) | NFKB1NFKB2RELA | |
| SCHEMBL23824589 | 0.92 | — | — | |
| SCHEMBL23824599 | 0.92 | — | — | |
| SCHEMBL25251620 | 0.92 | CTSS (0.48) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230033285-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | THE SCRIPPS RESEARCH INSTITUTE | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230033285-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | ACE, ACE2, TMPRSS2 | NFKB1 1311/4885NFKB2 1215/4885RELA 1705/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.