Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 2/20 | 0.48 |
| ▸ | CTSK | P43235 | 2/20 | 0.48 |
| ▸ | CTSL | P07711 | 3/20 | 0.45 |
| ▸ | CTSB | P07858 | 2/20 | 0.45 |
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29062690 | 1.00 | CTSS (0.48) | CTSSCTSKCTSLCTSBAAK1 | |
| SCHEMBL23836557 | 1.00 | CTSS (0.48) | CTSSCTSKCTSLCTSBAAK1 | |
| SCHEMBL23824564 | 0.94 | CTSL (0.51) | CTSSCTSKCTSLCTSBAAK1 | |
| SCHEMBL23824272 | 0.94 | CTSL (0.51) | CTSSCTSKCTSLCTSBAAK1 | |
| SCHEMBL23824275 | 0.94 | CTSL (0.51) | CTSSCTSKCTSLCTSBAAK1 | |
| SCHEMBL23824270 | 0.94 | CTSL (0.51) | CTSSCTSKCTSLCTSBAAK1 | |
| SCHEMBL24021092 | 0.92 | CTSL (0.49) | CTSSCTSKCTSLCTSBAAK1 | |
| SCHEMBL29062975 | 0.92 | CTSL (0.49) | CTSSCTSKCTSLCTSBAAK1 | |
| SCHEMBL29062972 | 0.92 | CTSL (0.49) | CTSSCTSKCTSLCTSBAAK1 | |
| SCHEMBL24584247 | 0.92 | NFKB1 (0.41) | CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116685576-A | Cysteine protease inhibitors and methods of use thereof | 美商帕迪斯生物科学公司 | 2023-09-01 | — | — | CN | disclosed |
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | Pardes Biosciences, Inc. | 2023-07-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230212152-A1 | INHIBITORS OF CYSTEINE PROTEASES AND METHODS OF USE THEREOF | CTRL, CTSL, CTSV | CTSS 7/4885CTSK 46/4885CTSL 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.