Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 2/20 | 0.38 |
| ▸ | CCR2 | P41597 | 1/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | MMP1 | P03956 | 3/20 | 0.35 |
| ▸ | MMP3 | P08254 | 2/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
| ▸ | MMP7 | P09237 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6730325 | 1.00 | CTSD (0.38) | CTSDCCR2ARL3MBTL1MMP1 | |
| SCHEMBL5872369 | 0.94 | CCR2 (0.43) | CTSDCCR2ARMMP1MMP3 | |
| SCHEMBL6732243 | 0.88 | AR (0.44) | AR | |
| SCHEMBL25134503 | 0.85 | L3MBTL1 (0.34) | CCR2L3MBTL1 | |
| SCHEMBL26724983 | 0.78 | L3MBTL1 (0.37) | CCR2L3MBTL1MMP1MMP3MMP2 | |
| SCHEMBL10210464 | 0.78 | — | — | |
| SCHEMBL14752921 | 0.78 | — | — | |
| SCHEMBL1967238 | 0.78 | — | — | |
| Hydrochloric Acid SCHEMBL319092 | 0.78 | L3MBTL1 (0.32) | CCR2L3MBTL1 | |
| Hydrochloric Acid SCHEMBL4190974 | 0.77 | L3MBTL1 (0.37) | CCR2L3MBTL1MMP1MMP3MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230033285-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | THE SCRIPPS RESEARCH INSTITUTE | 2023-02-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230033285-A1 | Protease Inhibitors for Treatment of Coronavirus Infections | ACE, ACE2, TMPRSS2 | CTSD 67/4885CCR2 998/4885AR 1669/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.