Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.35 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.35 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.35 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.35 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.35 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.35 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | KCNN3 | Q9UGI6 | 9/20 | 0.35 |
| ▸ | KCNN1 | Q92952 | 2/20 | 0.35 |
| ▸ | KCNN2 | Q9H2S1 | 2/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.33 |
| ▸ | CDK9 | P50750 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21849245 | 0.79 | KDM4E (0.34) | PDE10AKDM4EKCNN3 | |
| SCHEMBL11608751 | 0.78 | PRKAB2 (0.49) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL21754101 | 0.78 | PDE10A (0.41) | PDE10AKDM4ECDK2KCNN3CCNT1 | |
| SCHEMBL21849086 | 0.78 | KDM4E (0.42) | PDE10AKDM4ECDK2KCNN3KCNN1 | |
| SCHEMBL12952976 | 0.77 | PDE10A (0.61) | PDE10AKDM4EKCNN3KCNN1KCNN2 | |
| SCHEMBL27114778 | 0.74 | CCNT1 (0.38) | PDE10AKDM4ECDK2KCNN3CCNT1 | |
| SCHEMBL27116430 | 0.74 | PDE10A (0.38) | PDE10AKDM4ECDK2KCNN3CCNT1 | |
| SCHEMBL14492447 | 0.72 | CDK2 (0.48) | PDE10AKDM4ECDK2KCNN3KCNN1 | |
| SCHEMBL22131142 | 0.71 | PRKAB2 (0.46) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL9911039 | 0.68 | DGAT1 (0.34) | PDE10APRKAB2PRKAG1PRKAA2PRKAA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230028336-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | PAHR THERAPEUTICS, INC. | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230028336-A1 | INDOLE AHR INHIBITORS AND USES THEREOF | AHR, ARNT, IDO1 | PDE10A 2875/4885KDM4E 923/4885PRKAB2 2612/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.