Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132773 | 0.89 | ALDH1A1 (0.78) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL7669070 | 0.85 | ALDH1A1 (0.67) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL22734055 | 0.83 | ALDH1A1 (0.64) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL7115522 | 0.83 | ALDH1A1 (0.64) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL4198688 | 0.83 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL11315920 | 0.83 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL126492 | 0.83 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL10604973 | 0.83 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL2756748 | 0.81 | ALDH1A1 (0.67) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL3225684 | 0.81 | ALDH1A1 (0.67) | ALDH1A1CYP3A4KMT2AMEN1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023001223-A1 | COMPOUNDS AND COMPOSITIONS FOR TARGETED THERAPY OF RENAL DISEASES | SHANGHAI MICURX PHARMACEUTICAL CO., LTD. (CN) | 2023-01-26 | — | — | WO | disclosed |