Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | IDH1 | O75874 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL132773 | 0.91 | ALDH1A1 (0.78) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL126492 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL10604973 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL11315920 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL4198688 | 0.84 | ALDH1A1 (0.69) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL873414 | 0.83 | ALDH1A1 (0.67) | ALDH1A1CYP3A4CA2MAPT | |
| SCHEMBL7669070 | 0.83 | ALDH1A1 (0.67) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL10017478 | 0.83 | ALDH1A1 (0.67) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| SCHEMBL7184720 | 0.83 | ALDH1A1 (0.67) | ALDH1A1CYP3A4KMT2AMEN1CA2 | |
| P-Xylene SCHEMBL9685877 | 0.83 | ALDH1A1 (0.67) | ALDH1A1CYP3A4CA2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100056623-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2010-03-04 | — | — | US | claimed |
| EP-1841761-A4 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARM CORP (KR) | 2008-10-29 | — | — | EP | claimed |
| EP-1841761-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | Chong Kun Dang Pharmaceutical Corp. (KR) | 2007-10-10 | — | — | EP | claimed |
| WO-2006080591-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2006-08-03 | — | — | WO | claimed |
| US-20100056623-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP. (KR) | 2010-03-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100056623-A1 | FUMAGILLOL DERIVATIVES OR METHOD FOR PREPARATION OF FUMAGILLOL DERIVATIVES, AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | FAH, FH, ALDH1A2 | ALDH1A1 269/4885CYP3A4 1265/4885KMT2A 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.