Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UCHL1 | P09936 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | GHSR | Q92847 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.46 |
| ▸ | PGR | P06401 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.45 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4920445 | 0.99 | UCHL1 (0.50) | UCHL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2470474 | 0.82 | HDAC1 (0.50) | UCHL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2470476 | 0.82 | HDAC1 (0.50) | UCHL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2492550 | 0.82 | HDAC1 (0.50) | UCHL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL2472514 | 0.81 | ADRB2 (0.60) | UCHL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| Hydrochloric Acid SCHEMBL4922779 | 0.80 | ADRB2 (0.59) | UCHL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL19770591 | 0.79 | POLB (0.46) | UCHL1ALDH1A1SMN1; SMN2MAPTLMNA | |
| SCHEMBL4863436 | 0.77 | SIGMAR1 (0.60) | ALDH1A1GHSRSIGMAR1ADRB2ADRB1 | |
| Hydrochloric Acid SCHEMBL4870286 | 0.76 | SIGMAR1 (0.58) | ALDH1A1GHSRSIGMAR1ADRB2ADRB1 | |
| SCHEMBL2466084 | 0.75 | FFAR1 (0.51) | UCHL1ALDH1A1SMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2371814-A1 | Aminoethylaromatic compounds suitable for treating disorders that respond to modulation of the dopamine D3 receptor | Abbott GmbH & Co. KG (DE) | 2011-10-05 | — | — | EP | disclosed |