⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1702353 | 0.83 | HMGCR (0.30) | — | |
| SCHEMBL5842338 | 0.82 | APLNR (0.37) | — | |
| SCHEMBL24724318 | 0.82 | TRPV4 (0.36) | — | |
| SCHEMBL24721126 | 0.79 | — | — | |
| SCHEMBL27964769 | 0.79 | NPC1 (0.30) | — | |
| SCHEMBL12091514 | 0.79 | LMNA (0.31) | — | |
| SCHEMBL22149025 | 0.77 | — | — | |
| SCHEMBL824021 | 0.76 | TSHR (0.32) | — | |
| SCHEMBL21452309 | 0.76 | — | — | |
| SCHEMBL24966653 | 0.75 | APLNR (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230022157-A1 | PHARMACEUTICAL COMPOUNDS FOR THE TREATMENT OF COMPLEMENT FACTOR D MEDICAL DISORDERS | ACHILLION PHARMACEUTICALS, INC. (US) | 2023-01-26 | — | — | US | disclosed |