Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 6/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 6/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 4/20 | 0.42 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 6/20 | 0.41 |
| ▸ | FAAH | O00519 | 5/20 | 0.41 |
| ▸ | TIPARP | Q7Z3E1 | 1/20 | 0.39 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24967944 | 1.00 | CHRM2 (0.43) | CHRM2CHRM1CHRM3TRPA1CHRM4 | |
| SCHEMBL24967938 | 0.86 | TRPA1 (0.54) | TRPA1TIPARP | |
| SCHEMBL30164987 | 0.86 | TRPA1 (0.54) | TRPA1TIPARP | |
| SCHEMBL29165932 | 0.80 | SLC6A9 (0.47) | TIPARPSLC6A9 | |
| SCHEMBL29165852 | 0.79 | TIPARP (0.40) | CHRM4TIPARPSLC6A9 | |
| SCHEMBL24968205 | 0.79 | TRPA1 (0.42) | TRPA1TIPARP | |
| SCHEMBL24967934 | 0.79 | TRPA1 (0.42) | TRPA1TIPARP | |
| SCHEMBL24968206 | 0.79 | TRPA1 (0.42) | TRPA1TIPARP | |
| SCHEMBL24968226 | 0.78 | CHRM4 (0.45) | CHRM2CHRM1CHRM3CHRM4TIPARP | |
| SCHEMBL24968434 | 0.78 | CHRM4 (0.45) | CHRM2CHRM1CHRM3CHRM4TIPARP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |