Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LGALS3 | P17931 | 2/20 | 0.35 |
| ▸ | ALB | P02768 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28277909 | 0.80 | MAOA (0.40) | NOTUMDGAT1KDM4EALDH1A1TP53 | |
| SCHEMBL28277910 | 0.80 | MAOA (0.40) | NOTUMDGAT1KDM4EALDH1A1TP53 | |
| SCHEMBL15199190 | 0.79 | TP53 (0.37) | ALOX15DGAT1KDM4EALDH1A1TP53 | |
| SCHEMBL22736855 | 0.79 | DGAT1 (0.40) | DGAT1KDM4EALDH1A1TP53GLA | |
| SCHEMBL18161586 | 0.78 | GABRP (0.40) | ALOX15DGAT1KDM4EALDH1A1TP53 | |
| SCHEMBL22906161 | 0.78 | NOTUM (0.49) | NOTUMPARP14NPSR1ALOX15 | |
| SCHEMBL14722019 | 0.76 | DGAT1 (0.38) | DGAT1ALDH1A1LGALS3 | |
| SCHEMBL18605700 | 0.70 | KMT2A (0.59) | NPSR1ALDH1A1POLB | |
| SCHEMBL16579400 | 0.70 | NOTUM (0.52) | NOTUMNPSR1ALOX15 | |
| SCHEMBL18159138 | 0.69 | MEN1 (0.41) | POLBLGALS3ALBFOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023007481-A1 | WATER SOLUBLE PRODRUG, CONJUGATES AND USES THEREOF | RAMOT AT TEL-AVIV UNIVERSITY LTD. (IL) | 2023-02-02 | — | — | WO | disclosed |