Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 2/20 | 0.55 |
| ▸ | KDR | P35968 | 2/20 | 0.49 |
| ▸ | BRAF | P15056 | 2/20 | 0.49 |
| ▸ | EGFR | P00533 | 7/20 | 0.48 |
| ▸ | ITK | Q08881 | 4/20 | 0.48 |
| ▸ | BLK | P51451 | 2/20 | 0.46 |
| ▸ | BRD4 | O60885 | 4/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.45 |
| ▸ | BTK | Q06187 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968529 | 0.87 | BRAF (0.49) | KDRBRAFEGFRITKBRD4 | |
| SCHEMBL24969515 | 0.86 | FFAR1 (0.59) | FFAR1KDRBRAF | |
| SCHEMBL24969112 | 0.85 | FFAR1 (0.53) | FFAR1KDRBRAFEGFRITK | |
| SCHEMBL24968522 | 0.85 | BRD4 (0.52) | KDRBRAFEGFRITKBLK | |
| SCHEMBL24968532 | 0.83 | TGM2 (0.65) | EGFRITKBLKBRD4TGM2 | |
| SCHEMBL24969114 | 0.79 | TGM2 (0.57) | FFAR1KDRBRAFEGFRBRD4 | |
| SCHEMBL24968527 | 0.78 | TGM2 (0.60) | KDRBRAFBLKBRD4TGM2 | |
| SCHEMBL22731792 | 0.78 | TGM2 (0.50) | KDRBRAFEGFRBLKTGM2 | |
| SCHEMBL13154807 | 0.78 | TGM2 (0.59) | KDREGFRTGM2 | |
| SCHEMBL30684820 | 0.78 | TGM2 (0.59) | KDREGFRTGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |