Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 3/20 | 0.65 |
| ▸ | BLK | P51451 | 1/20 | 0.56 |
| ▸ | PNLIP | P16233 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 7/20 | 0.53 |
| ▸ | EGFR | P00533 | 4/20 | 0.52 |
| ▸ | BTK | Q06187 | 4/20 | 0.52 |
| ▸ | ITK | Q08881 | 1/20 | 0.51 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | JAK3 | P52333 | 1/20 | 0.49 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.49 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.49 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.49 |
| ▸ | KCNQ1 | P51787 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968527 | 0.89 | TGM2 (0.60) | TGM2BLKPNLIPBRD4 | |
| SCHEMBL24968522 | 0.88 | BRD4 (0.52) | TGM2BLKPNLIPBRD4EGFR | |
| SCHEMBL24969114 | 0.87 | TGM2 (0.57) | TGM2PNLIPBRD4EGFR | |
| SCHEMBL24969112 | 0.86 | FFAR1 (0.53) | TGM2BLKBRD4EGFRBTK | |
| SCHEMBL24968529 | 0.84 | BRAF (0.49) | TGM2PNLIPBRD4EGFRITK | |
| SCHEMBL24968520 | 0.83 | FFAR1 (0.55) | TGM2BLKBRD4EGFRBTK | |
| SCHEMBL22732029 | 0.81 | TGM2 (0.65) | TGM2BRD4EGFRBTKERBB2 | |
| SCHEMBL24968812 | 0.81 | EGFR (0.54) | TGM2EGFRITKERBB2 | |
| SCHEMBL24968531 | 0.80 | KDR (0.50) | TGM2BLKPNLIPBRD4EGFR | |
| SCHEMBL9017578 | 0.79 | TGM2 (1.00) | TGM2PNLIPEGFRERBB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |