Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TGM2 | P21980 | 2/20 | 0.48 |
| ▸ | BLK | P51451 | 2/20 | 0.48 |
| ▸ | BRD4 | O60885 | 6/20 | 0.48 |
| ▸ | EGFR | P00533 | 4/20 | 0.47 |
| ▸ | ITK | Q08881 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | MAP2K7 | O14733 | 1/20 | 0.46 |
| ▸ | BTK | Q06187 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968522 | 0.88 | BRD4 (0.52) | TGM2BLKBRD4EGFRITK | |
| SCHEMBL24969114 | 0.86 | TGM2 (0.57) | FFAR1TGM2BRD4EGFRBRAF | |
| SCHEMBL24968532 | 0.86 | TGM2 (0.65) | TGM2BLKBRD4EGFRITK | |
| SCHEMBL24968520 | 0.85 | FFAR1 (0.55) | FFAR1TGM2BLKBRD4EGFR | |
| SCHEMBL26217593 | 0.83 | MAP2K7 (0.58) | MEN1KMT2ATGM2EGFRITK | |
| SCHEMBL24968527 | 0.81 | TGM2 (0.60) | TGM2BLKBRD4BRAFKDR | |
| SCHEMBL24969052 | 0.81 | EGFR (0.55) | FFAR1EGFRITK | |
| SCHEMBL24968529 | 0.79 | BRAF (0.49) | TGM2BRD4EGFRITKBRAF | |
| SCHEMBL18741865 | 0.77 | BLK (0.85) | BLKEGFRITKBTK | |
| SCHEMBL29690981 | 0.77 | BLK (0.85) | BLKEGFRITKBTK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |