Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 11/20 | 0.46 |
| ▸ | ITK | Q08881 | 6/20 | 0.46 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.44 |
| ▸ | BRAF | P15056 | 1/20 | 0.42 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968810 | 0.88 | SCN9A (0.41) | EGFRITKSCN9ASCN5A | |
| SCHEMBL24968542 | 0.88 | EGFR (0.49) | EGFRITKBRAFKDRMET | |
| SCHEMBL24968822 | 0.88 | SCN9A (0.47) | EGFRITKSCN9ABRAFKDR | |
| SCHEMBL24968806 | 0.86 | TBK1 (0.42) | SCN9ASCN5A | |
| SCHEMBL24968537 | 0.86 | P2RX4 (0.51) | EGFRITKSCN9A | |
| SCHEMBL24968847 | 0.85 | SCN9A (0.44) | SCN9ASCN5AMET | |
| SCHEMBL24968543 | 0.84 | BRAF (0.45) | EGFRITKSCN9ABRAFKDR | |
| SCHEMBL28426333 | 0.83 | EGFR (0.49) | EGFRITKSCN9ABRAFKDR | |
| SCHEMBL24969053 | 0.80 | EGFR (0.46) | EGFRITKBRAFKDR | |
| SCHEMBL24969057 | 0.80 | SCN9A (0.44) | SCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |