Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 8/20 | 0.51 |
| ▸ | EGFR | P00533 | 6/20 | 0.50 |
| ▸ | ITK | Q08881 | 4/20 | 0.50 |
| ▸ | GRM4 | Q14833 | 5/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968542 | 0.89 | EGFR (0.49) | EGFRITK | |
| SCHEMBL24968534 | 0.86 | EGFR (0.46) | EGFRITKSCN9A | |
| SCHEMBL24968543 | 0.85 | BRAF (0.45) | EGFRITKSCN9A | |
| SCHEMBL28885488 | 0.83 | EGFR (0.61) | EGFRITK | |
| SCHEMBL28372149 | 0.81 | TGM2 (0.50) | EGFR | |
| SCHEMBL24968822 | 0.80 | SCN9A (0.47) | EGFRITKSCN9A | |
| SCHEMBL24969142 | 0.79 | EGFR (0.44) | EGFRITK | |
| SCHEMBL20463368 | 0.76 | SCN9A (0.47) | P2RX4GRM4SCN9A | |
| SCHEMBL28376476 | 0.75 | EGFR (0.58) | EGFRITK | |
| SCHEMBL24969095 | 0.74 | EGFR (0.50) | EGFRITK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |