Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRAF | P15056 | 1/20 | 0.45 |
| ▸ | KDR | P35968 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 9/20 | 0.45 |
| ▸ | ITK | Q08881 | 5/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.43 |
| ▸ | MET | P08581 | 1/20 | 0.41 |
| ▸ | FLT3 | P36888 | 1/20 | 0.41 |
| ▸ | TGM2 | P21980 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969142 | 0.88 | EGFR (0.44) | BRAFKDREGFRITKEPHX2 | |
| SCHEMBL24968542 | 0.87 | EGFR (0.49) | BRAFKDREGFRITKMET | |
| SCHEMBL24968537 | 0.85 | P2RX4 (0.51) | EGFRITKSCN9A | |
| SCHEMBL24968534 | 0.84 | EGFR (0.46) | BRAFKDREGFRITKSCN9A | |
| SCHEMBL24968822 | 0.78 | SCN9A (0.47) | BRAFKDREGFRITKSCN9A | |
| SCHEMBL24969099 | 0.76 | EGFR (0.52) | BRAFKDREGFRITKEPHX2 | |
| SCHEMBL24969092 | 0.75 | EGFR (0.51) | BRAFKDREGFRITKEPHX2 | |
| SCHEMBL20554330 | 0.74 | PDE4D (0.48) | KDREGFREPHX2MET | |
| SCHEMBL20608945 | 0.74 | PDE4D (0.48) | KDREGFREPHX2MET | |
| SCHEMBL20554331 | 0.74 | PDE4D (0.48) | KDREGFREPHX2MET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |