Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 4/20 | 0.42 |
| ▸ | DCPS | Q96C86 | 2/20 | 0.38 |
| ▸ | DHFR | P00374 | 1/20 | 0.38 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 4/20 | 0.37 |
| ▸ | HTR2C | P28335 | 4/20 | 0.37 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10503371 | 0.87 | MCHR1 (0.48) | MCHR1DCPSDHFRRIPK1HTR2C | |
| SCHEMBL20472331 | 0.78 | RIPK1 (0.49) | MCHR1RIPK1SCN9AHTR2CSCN5A | |
| SCHEMBL29786503 | 0.78 | RIPK1 (0.49) | MCHR1RIPK1SCN9AHTR2CSCN5A | |
| SCHEMBL24074790 | 0.75 | CYP3A4 (0.46) | — | |
| SCHEMBL24018847 | 0.75 | RIPK1 (0.52) | RIPK1SCN9ASCN5AKDM5AKDM4C | |
| SCHEMBL24968796 | 0.74 | SCN9A (0.42) | SCN9AHTR2CSCN5AKDM5AKDM4C | |
| SCHEMBL20554482 | 0.73 | HSP90AA1 (0.40) | MCHR1HTR2CKDM5AKDM4CKDM5B | |
| SCHEMBL3798519 | 0.73 | ALDH1A1 (0.53) | MCHR1DCPSDHFRRIPK1HTR2C | |
| SCHEMBL23493020 | 0.73 | ALDH1A1 (0.53) | MCHR1DCPSDHFRRIPK1HTR2C | |
| SCHEMBL24968800 | 0.72 | CDK2 (0.38) | MCHR1DCPSDHFRSCN9ASCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |