Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 7/20 | 0.42 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.42 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | HTR2C | P28335 | 2/20 | 0.39 |
| ▸ | HTR2B | P41595 | 2/20 | 0.39 |
| ▸ | TLR9 | Q9NR96 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.38 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
| ▸ | ACACB | O00763 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2546337 | 0.88 | HTR2C (0.47) | HTR2AHTR2CHTR2BTLR9TLR8 | |
| SCHEMBL22069559 | 0.85 | PARP10 (0.45) | HTR2AHTR2CHTR2B | |
| SCHEMBL13419711 | 0.79 | TLR9 (0.43) | HTR2AHTR2BTLR9TLR8TLR7 | |
| SCHEMBL24968528 | 0.79 | KDM4C (0.53) | SCN9ASCN5AKDM5AKDM4CKDM5B | |
| SCHEMBL30152356 | 0.78 | S1PR4 (0.48) | SCN9ASCN5A | |
| SCHEMBL24968797 | 0.77 | SCN9A (0.43) | SCN9ASCN5ALRRK2 | |
| SCHEMBL24969558 | 0.76 | SCN9A (0.49) | SCN9ASCN5AKDM5AKDM4CKDM5B | |
| SCHEMBL30152321 | 0.76 | SCN9A (0.49) | SCN9ASCN5AKDM5AKDM4CKDM5B | |
| SCHEMBL24074790 | 0.75 | CYP3A4 (0.46) | — | |
| SCHEMBL28844733 | 0.75 | HTR2C (0.43) | HTR2AHTR2CHTR2BTLR9TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |