Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDH2 | P48735 | 1/20 | 0.54 |
| ▸ | LCK | P06239 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.45 |
| ▸ | CDK2 | P24941 | 6/20 | 0.43 |
| ▸ | CDK4 | P11802 | 4/20 | 0.43 |
| ▸ | CCND1 | P24385 | 4/20 | 0.43 |
| ▸ | CCNE1 | P24864 | 4/20 | 0.43 |
| ▸ | CDK1 | P06493 | 3/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 3/20 | 0.43 |
| ▸ | CCND3 | P30281 | 3/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 3/20 | 0.43 |
| ▸ | ULK1 | O75385 | 1/20 | 0.42 |
| ▸ | IKBKB | O14920 | 1/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.42 |
| ▸ | MAPK7 | Q13164 | 1/20 | 0.42 |
| ▸ | PIM1 | P11309 | 1/20 | 0.41 |
| ▸ | CCNK | O75909 | 1/20 | 0.41 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20145210 | 0.82 | IL1B (0.49) | CDK2CCNE1CCNKCDK12 | |
| SCHEMBL18607391 | 0.82 | ULK1 (0.55) | ULK1MAPK1HDAC1 | |
| SCHEMBL29820852 | 0.81 | CCNE1 (0.57) | CDK2CDK4CCND1CCNE1CDK1 | |
| SCHEMBL16730436 | 0.81 | CCR6 (0.58) | IDH2CDK2CCNA2PIM1CCNK | |
| SCHEMBL26830431 | 0.80 | MAPK1 (0.62) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL31619954 | 0.80 | CCR6 (0.47) | CDK2CDK4CCND1CCNE1CDK1 | |
| SCHEMBL2950329 | 0.79 | HDAC1 (0.47) | CDK2CDK4CCND1CDK1CCNB1 | |
| SCHEMBL31619971 | 0.78 | MAPK1 (0.56) | IDH2ULK1IKBKBMAPK1 | |
| SCHEMBL31350462 | 0.77 | IDH2 (0.51) | IDH2LCKMAPK14SSTR4CDK2 | |
| SCHEMBL11989612 | 0.77 | HRH4 (0.45) | IDH2SSTR4CDK2CDK4CCND1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |