Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 4/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26151635 | 0.88 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHRH4HRH3CXCR3 | |
| SCHEMBL18176128 | 0.85 | POLB (0.51) | SMN1; SMN2LMNAPOLBCXCR3 | |
| SCHEMBL13107612 | 0.84 | SCN10A (0.51) | POLB | |
| SCHEMBL31013268 | 0.83 | SMN1; SMN2 (0.50) | SMN1; SMN2LMNAHRH4HRH3POLB | |
| SCHEMBL24970195 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2LMNAHRH4HRH3POLB | |
| SCHEMBL14136353 | 0.83 | SMN1; SMN2 (0.70) | SMN1; SMN2LMNAPOLBMAPTMEN1 | |
| SCHEMBL26958284 | 0.82 | SMN1; SMN2 (0.49) | SMN1; SMN2LMNAHRH4HRH3POLB | |
| SCHEMBL2575981 | 0.81 | ADRB1 (0.50) | SMN1; SMN2LMNAPOLBCXCR3MAPT | |
| SCHEMBL26958209 | 0.81 | SMN1; SMN2 (0.48) | SMN1; SMN2LMNAHRH4HRH3POLB | |
| SCHEMBL31013249 | 0.80 | CXCR3 (0.52) | SMN1; SMN2LMNAHRH4HRH3POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023006013-A1 | NOVEL PARP7 INHIBITOR AND USE THEREOF | 上海齐鲁制药研究中心有限公司 | 2023-02-02 | — | — | WO | disclosed |