SCHEMBL24969042

SCHEMBL24969042

O=C(NS(=O)(=O)C1CC1)c1ccc(OF)c(F)c1

nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 18/20 0.45
SCN2B O60939 2/20 0.45
SCN1B Q07699 2/20 0.45
SCN5A Q14524 6/20 0.44
SCN1A P35498 1/20 0.44
STS P08842 1/20 0.43
HTR7 P34969 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24968523 0.78 SCN9A (0.66) SCN9ASCN5ASCN1A
SCHEMBL30436806 0.74 SCN2B (0.58) SCN9ASCN2BSCN1BSCN5ASCN1A
SCHEMBL31215388 0.71 SCN9A (0.48) SCN9ASCN2BSCN1BSCN5ASCN1A
SCHEMBL17113311 0.70 OGG1 (0.47) SCN9ASCN5A
SCHEMBL29865510 0.70 MEN1 (0.49) SCN9ASCN5A
SCHEMBL3808268 0.70 HDAC3 (0.50) SCN9ASCN5A
SCHEMBL31215393 0.69 SCN9A (0.46) SCN9ASCN2BSCN1BSCN5ASCN1A
SCHEMBL17346271 0.69 RAB9A (0.70)
SCHEMBL20118985 0.69 HDAC8 (0.58) SCN9ASCN2BSCN1BSCN5ASCN1A
SCHEMBL16759704 0.68 HPGD (0.58) SCN9ASCN5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023009785-A1 TEAD INHIBITORS AND USES THEREOF CEDILLA THERAPEUTICS, INC. (US) 2023-02-02 WO disclosed