Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28504448 | 0.89 | MAOA (0.39) | MAOAMAOBDRD2DRD1HTR2A | |
| SCHEMBL21752368 | 0.79 | ACHE (0.35) | — | |
| SCHEMBL25713419 | 0.78 | ACHE (0.34) | HTR2A | |
| SCHEMBL27002212 | 0.78 | CYP3A4 (0.34) | MAOAMAOBDRD2DRD1HTR2A | |
| SCHEMBL25530815 | 0.78 | ACHE (0.34) | — | |
| SCHEMBL31039563 | 0.78 | ACHE (0.34) | — | |
| SCHEMBL21955253 | 0.77 | SLC5A1 (0.30) | — | |
| SCHEMBL9868328 | 0.76 | SMN1; SMN2 (0.45) | — | |
| SCHEMBL34464431 | 0.75 | PDE4A (0.31) | — | |
| SCHEMBL21955272 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |