Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 9/20 | 0.34 |
| ▸ | IL1RN | P18510 | 1/20 | 0.32 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.32 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31039563 | 1.00 | ACHE (0.34) | ACHEIL1RNERAP2ERAP1LMNA | |
| SCHEMBL18181738 | 0.89 | LMNA (0.36) | IL1RNERAP2ERAP1LMNAMAPT | |
| SCHEMBL17712111 | 0.85 | ACHE (0.34) | ACHELMNAMAPT | |
| SCHEMBL21752368 | 0.79 | ACHE (0.35) | ACHE | |
| SCHEMBL24969045 | 0.78 | MAOA (0.33) | — | |
| SCHEMBL25713419 | 0.78 | ACHE (0.34) | ACHE | |
| SCHEMBL34464431 | 0.75 | PDE4A (0.31) | — | |
| SCHEMBL17041206 | 0.74 | MAPT (0.35) | LMNAMAPT | |
| SCHEMBL29661294 | 0.74 | MAPT (0.35) | LMNAMAPT | |
| SCHEMBL21955253 | 0.74 | SLC5A1 (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023078411-A1 | AZASPIRO COMPOUND | 南京明德新药研发有限公司 | 2023-05-11 | — | — | WO | disclosed |