Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 13/20 | 0.49 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.49 |
| ▸ | PDE4A | P27815 | 3/20 | 0.45 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.45 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.45 |
| ▸ | KDM5A | P29375 | 1/20 | 0.41 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.41 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30152321 | 1.00 | SCN9A (0.49) | SCN9ASCN5APDE4APDE4BPDE4C | |
| SCHEMBL1861841 | 0.90 | PDE4B (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24968528 | 0.86 | KDM4C (0.53) | SCN9ASCN5APDE4APDE4BPDE4C | |
| SCHEMBL24968523 | 0.80 | SCN9A (0.66) | SCN9ASCN5A | |
| SCHEMBL20189249 | 0.80 | PDE4B (0.50) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL28033753 | 0.78 | PDE4B (0.59) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL20463367 | 0.77 | SLC6A9 (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL24968525 | 0.77 | KDM4C (0.53) | SCN9ASCN5APDE4APDE4BPDE4C | |
| SCHEMBL2090601 | 0.76 | PDE4B (0.60) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4278555 | 0.76 | PDE4B (0.63) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |