Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.53 |
| ▸ | KDM5A | P29375 | 1/20 | 0.53 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 3/20 | 0.47 |
| ▸ | RBP4 | P02753 | 1/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24968525 | 0.90 | KDM4C (0.53) | KDM4CKDM5AKDM5BSCN9ASCN5A | |
| SCHEMBL15968784 | 0.89 | LMNA (0.55) | KDM4CKDM5ALMNAMAPK1HTT | |
| SCHEMBL10148081 | 0.87 | MAP4K4 (0.54) | KDM4CLMNAMAPK1HTTRAB9A | |
| SCHEMBL30152321 | 0.86 | SCN9A (0.49) | KDM4CKDM5AKDM5BSCN9ASCN5A | |
| SCHEMBL24969558 | 0.86 | SCN9A (0.49) | KDM4CKDM5AKDM5BSCN9ASCN5A | |
| SCHEMBL24968523 | 0.81 | SCN9A (0.66) | SCN9ASCN5A | |
| SCHEMBL24800516 | 0.80 | KDM4C (0.48) | KDM4CKDM5AKDM5BSCN9ASCN5A | |
| SCHEMBL24968796 | 0.79 | SCN9A (0.42) | KDM4CKDM5AKDM5BSCN9ASCN5A | |
| SCHEMBL662159 | 0.78 | TTR (0.50) | KDM4CKDM5ALMNAMAPK1HTT | |
| SCHEMBL20463367 | 0.77 | SLC6A9 (0.53) | LMNAMAPK1HTTRAB9APDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |
| WO-2023009785-A1 | TEAD INHIBITORS AND USES THEREOF | CEDILLA THERAPEUTICS, INC. (US) | 2023-02-02 | — | — | WO | disclosed |