Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRD1 | P41143 | 10/20 | 0.68 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.68 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.68 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.68 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.68 |
| ▸ | SLC22A1 | O15245 | 2/20 | 0.68 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.68 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.68 |
| ▸ | MEN1 | O00255 | 1/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24969242 | 1.00 | OPRD1 (0.68) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL24969483 | 1.00 | OPRD1 (0.68) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| Hydrochloric Acid SCHEMBL30206730 | 0.99 | OPRD1 (0.67) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| Hydrochloric Acid SCHEMBL28564704 | 0.99 | OPRD1 (0.67) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| Hydrochloric Acid SCHEMBL28572513 | 0.99 | OPRD1 (0.67) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL22662432 | 0.81 | OPRM1 (0.56) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| SCHEMBL20399445 | 0.81 | OPRM1 (0.56) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| (R,R)-Tramadol SCHEMBL1593740 | 0.81 | SLC6A2 (1.00) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| (R,R)-Tramadol SCHEMBL11984200 | 0.81 | SLC6A2 (1.00) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 | |
| (R,R)-Tramadol SCHEMBL12831358 | 0.81 | SLC6A2 (1.00) | OPRD1OPRK1SLC6A2SLC6A4OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230027752-A1 | OPIOID RECEPTOR AGONIST, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | FUDAN UNIVERSITY (CN) | 2023-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230027752-A1 | OPIOID RECEPTOR AGONIST, PREPARATION METHOD THEREFOR AND PHARMACEUTICAL USE THEREOF | OPRM1, OPRD1, OPRL1 | OPRD1 2/4885OPRK1 4/4885SLC6A2 738/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.