Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 19/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2932988 | 0.92 | CRHR1 (0.38) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL2502636 | 0.89 | CRHR1 (0.39) | CRHR1KDM4EHPGD | |
| SCHEMBL2930712 | 0.83 | CRHR1 (0.39) | CRHR1KDM4EHPGD | |
| SCHEMBL12409295 | 0.80 | CRHR1 (0.40) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL15103887 | 0.80 | CRHR1 (0.39) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL22335453 | 0.80 | HPGD (0.34) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL2180543 | 0.80 | CRHR1 (0.54) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL2178265 | 0.79 | CRHR1 (0.39) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL15103992 | 0.79 | CRHR1 (0.40) | CRHR1KDM4EALDH1A1HPGD | |
| SCHEMBL2497127 | 0.78 | CRHR1 (0.38) | CRHR1KDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1159336-B2 | INTRINSICALLY GEL-FREE, RANDOMLY BRANCHED POLYAMIDE | DSM IP ASSETS BV (NL) | 2010-09-15 | — | — | EP | claimed |
| EP-1159336-B1 | INTRINSICALLY GEL-FREE, RANDOMLY BRANCHED POLYAMIDE | DSM NV (NL) | 2002-09-25 | — | — | EP | claimed |
| US-8030304-B2 | Thiazole pyrazolopyrimidines CRF1 receptor antagonists | ELI LILLY AND COMPANY (US) | 2011-10-04 | — | — | US | disclosed |
| EP-2094709-B1 | THIAZOLE PYRAZOLOPYRIMIDINES AS CRF1 RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2010-09-15 | — | — | EP | disclosed |
| US-20100222339-A1 | Thiazole pyrazolopyrimidines CRF1 receptor antagonists | ELI LILLY AND COMPANY | 2010-09-02 | — | — | US | disclosed |
| CN-1406233-A | Medicine for viral diseases | BAYER AG (DE) | 2003-03-26 | — | — | CN | disclosed |
| EP-1286974-A2 | MEDICAMENT FOR VIRAL DISEASES | Bayer Aktiengesellschaft (DE) | 2003-03-05 | — | — | EP | disclosed |
| WO-2002020509-A2 | MEDICAMENTS AGAINST VIRAL INFECTIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2002-03-14 | — | — | WO | disclosed |
| WO-2001064755-A2 | ISOXAZOLE GEGEN VIRALE ERKRANKUNGEN | BAYER AKTIENGESELLSCHAFT (DE) | 2001-09-07 | — | — | WO | disclosed |
| EP-0563731-B1 | Medicaments containing polyhydroxymethylene-derivatives, process for their manufacture and use thereof | HOECHST AG (DE) | 1995-11-15 | — | — | EP | disclosed |
| CN-1027169-C | Process for preparing epipodophyllotoxin glucoside 4' -phosphate derivatives | BRISTOL MYERS SQUIBB CO (US) | 1994-12-28 | — | — | CN | disclosed |
| CN-1024317-C | Antifungal agents based on amides containing phenyl group | RHONE POULENC AGROCHIMIE (FR) | 1994-04-27 | — | — | CN | disclosed |
| EP-0563731-A1 | Medicaments containing polyhydroxymethylene-derivatives, process for their manufacture and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1993-10-06 | — | — | EP | disclosed |
| CN-1017049-B | PROCESS FOR PREPARING 5,6-DIHYDRO-2-(SUBSTITUTED PHENYL) 1,2,4 TRIAZINE-3,5(2H,4H)-DIONES | JANSSEN PHARMACEUTICA NV (BE) | 1992-06-17 | — | — | CN | disclosed |
| CN-1040792-A | ANTIFUNGAL AGENTS BASED ON AMIDES CONTAINING PHENYL GROUP | RHONE POULENC AGROCHIMIE (FR) | 1990-03-28 | — | — | CN | disclosed |
| CN-1036957-A | It is antiviral with imidazolidine [1,4] benzodiazepine-2-ketone compounds also, | JANSSEN PHARMACEUTICA NV (BE) | 1989-11-08 | — | — | CN | disclosed |
| CN-87100531-A | 5,6-dihydro-2-(phenyl of replacement)-1,2,4-triazine-3,5 (2H, 4H)-two ketone | — | 1987-09-02 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100222339-A1 | Thiazole pyrazolopyrimidines CRF1 receptor antagonists | CRHR1, CRH, CRHR2 | CRHR1 1/4885KDM4E 4562/4885ALDH1A1 1482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.