Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | GPR6 | P46095 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.32 |
| ▸ | CNR2 | P34972 | 4/20 | 0.31 |
| ▸ | CNR1 | P21554 | 3/20 | 0.31 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143036 | 0.77 | CNR1 (0.47) | MAPTALDH1A1POLBMEN1KMT2A | |
| SCHEMBL31142946 | 0.75 | ADRB1 (0.43) | MAPTKDM4ENPC1ALDH1A1POLB | |
| SCHEMBL24970936 | 0.75 | ADRB1 (0.43) | MAPTKDM4ENPC1ALDH1A1POLB | |
| Hydrochloric Acid SCHEMBL30223275 | 0.74 | ADRB1 (0.42) | MAPTKDM4ENPC1ALDH1A1POLB | |
| SCHEMBL24511557 | 0.68 | SLC6A2 (0.42) | MAPTALDH1A1RAB9AKMT2ADRD2 | |
| SCHEMBL24969920 | 0.63 | CNR1 (0.49) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL31143026 | 0.63 | CNR1 (0.49) | KDM4EALDH1A1POLBMEN1KMT2A | |
| SCHEMBL31143096 | 0.62 | PPARA (0.36) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL24971015 | 0.62 | PPARA (0.36) | MAPTKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL23365940 | 0.61 | MAPT (0.46) | MAPTKDM4EALDH1A1ALOX15TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002011-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-01-26 | — | — | WO | disclosed |