Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.65 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.65 |
| ▸ | PARP1 | P09874 | 3/20 | 0.45 |
| ▸ | PDE2A | O00408 | 1/20 | 0.42 |
| ▸ | PDE6D | O43924 | 1/20 | 0.42 |
| ▸ | PDE8A | O60658 | 1/20 | 0.42 |
| ▸ | PDE5A | O76074 | 1/20 | 0.42 |
| ▸ | PDE9A | O76083 | 1/20 | 0.42 |
| ▸ | PDE8B | O95263 | 1/20 | 0.42 |
| ▸ | PDE6A | P16499 | 1/20 | 0.42 |
| ▸ | PDE6G | P18545 | 1/20 | 0.42 |
| ▸ | PDE4A | P27815 | 1/20 | 0.42 |
| ▸ | PDE6B | P35913 | 1/20 | 0.42 |
| ▸ | PDE6C | P51160 | 1/20 | 0.42 |
| ▸ | PDE1A | P54750 | 1/20 | 0.42 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31143069 | 1.00 | DAO (0.65) | DAOATAD2PARP1PDE2APDE6D | |
| SCHEMBL3364094 | 0.79 | DAO (1.00) | DAOATAD2PARP1PDE2APDE6D | |
| SCHEMBL30663285 | 0.79 | ATAD2 (1.00) | DAOATAD2PARP1PDE2APDE6D | |
| SCHEMBL24312059 | 0.78 | ATAD2 (0.64) | DAOATAD2PARP1PDE2APDE6D | |
| SCHEMBL2118566 | 0.77 | DAO (0.53) | DAOATAD2CASP6MEN1KMT2A | |
| SCHEMBL24390514 | 0.76 | ATAD2 (0.66) | DAOATAD2PARP1PDE2APDE6D | |
| SCHEMBL22016868 | 0.75 | ATAD2 (0.64) | DAOATAD2PARP1PDE2APDE6D | |
| SCHEMBL10689557 | 0.75 | DAO (0.59) | DAOATAD2PARP1PDE2APDE6D | |
| SCHEMBL21549789 | 0.75 | DAO (0.59) | DAOATAD2PARP1PDE2APDE6D | |
| SCHEMBL21551043 | 0.75 | ATAD2 (0.64) | DAOATAD2PARP1PDE2APDE6D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023002011-A1 | GRAM-NEGATIVE BACTERIA EFFLUX PUMP INHIBITORS | INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) (FR) | 2023-01-26 | — | — | WO | disclosed |