Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.31 |
| ▸ | NOS2 | P35228 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21493100 | 0.82 | KMT2A (0.31) | ALDH1A1MEN1KMT2A | |
| SCHEMBL21493142 | 0.81 | ALDH1A1 (0.32) | ALDH1A1 | |
| SCHEMBL1586910 | 0.78 | CA2 (0.33) | CA2ALDH1A1MAPTGAAMAPK1 | |
| SCHEMBL481256 | 0.77 | IDO1 (0.42) | ALDH1A1MAPTKDM4E | |
| SCHEMBL2037856 | 0.76 | NOTUM (0.38) | ALDH1A1PTPN1 | |
| SCHEMBL5442094 | 0.75 | CYP2A6 (0.34) | ALDH1A1MAPTMEN1KMT2APTPN1 | |
| SCHEMBL2497068 | 0.75 | MAPT (0.41) | ALDH1A1MAPTGAAMAPK1HTT | |
| SCHEMBL722683 | 0.75 | IDO1 (0.49) | ALDH1A1 | |
| SCHEMBL1430161 | 0.74 | PYCR1 (0.41) | ALDH1A1MAPTGAAMAPK1TSHR | |
| SCHEMBL5777588 | 0.74 | IDO1 (0.36) | HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8030499-B2 | 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 2011-10-04 | — | — | US | disclosed |