Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 4/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15131744 | 0.92 | SMN1; SMN2 (0.55) | SMN1; SMN2POLBNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL19431618 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL18731194 | 0.84 | SMN1; SMN2 (0.52) | SMN1; SMN2POLBNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL15490020 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBNPSR1L3MBTL1ATM | |
| SCHEMBL17190676 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBNPSR1L3MBTL1CHRNB2 | |
| SCHEMBL19104799 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBNPSR1L3MBTL1ATM | |
| SCHEMBL12197935 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBNPSR1L3MBTL1CHRNB2 | |
| SCHEMBL12764368 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBNPSR1L3MBTL1ALDH1A1 | |
| SCHEMBL13401071 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBNPSR1L3MBTL1CHRNB2 | |
| SCHEMBL17190672 | 0.82 | SMN1; SMN2 (0.53) | SMN1; SMN2POLBNPSR1L3MBTL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11572364-B2 | Pteridinone compounds and uses thereof | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2023-02-07 | — | — | US | disclosed |
| US-20170110671-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | SAMSUNG DISPLAY CO., LTD. (KR) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11572364-B2 | Pteridinone compounds and uses thereof | DPYD, PKD1, TYMP | SMN1; SMN2 1711/4885POLB 300/4885NPSR1 2323/4885 |
| US-20170110671-A1 | COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME | LOXL1, ELOVL1, LPO | SMN1; SMN2 1883/4885POLB 2423/4885NPSR1 4537/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.