N-Furfurylidene-P-Toluidine

N-Furfurylidene-P-Toluidine

SCHEMBL24974694

Cc1ccc(/N=C/c2ccco2)cc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 10/20 0.68
ALDH1A1 P00352 9/20 0.68
KMT2A Q03164 8/20 0.68
MEN1 O00255 7/20 0.68
GAA P10253 5/20 0.68
L3MBTL1 Q9Y468 4/20 0.68
MAPK1 P28482 4/20 0.68
TSHR P16473 3/20 0.68
ALOX12 P18054 2/20 0.68
HSD17B10 Q99714 2/20 0.68
NPSR1 Q6W5P4 2/20 0.68
ALOX15 P16050 2/20 0.68
ATM Q13315 1/20 0.68
ESR2 Q92731 1/20 0.68
POLB P06746 4/20 0.55
KDM4E B2RXH2 4/20 0.51
CASP1 P29466 1/20 0.49
CYP1A2 P05177 3/20 0.46
CYP2C9 P11712 3/20 0.46
CYP2C19 P33261 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3132675 0.82 ALDH1A1 (0.64) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL3132668 0.82 ALDH1A1 (0.64) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL21663529 0.82 ALDH1A1 (0.64) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL28028383 0.81 ALDH1A1 (0.63) MAPTALDH1A1KMT2AMEN1GAA
N-Furfurylidene-P-Anisidine SCHEMBL11377145 0.81 ALDH1A1 (0.62) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL24974695 0.81 MAPT (0.62) MAPTALDH1A1KMT2AMEN1GAA
N-Furfurylidene-M-Toluidine SCHEMBL24974696 0.81 ALDH1A1 (0.54) MAPTALDH1A1KMT2AMEN1GAA
N-Furfurylidene-P-Anisidine SCHEMBL7735571 0.81 ALDH1A1 (0.62) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL11818491 0.80 ALDH1A1 (0.61) MAPTALDH1A1KMT2AMEN1GAA
SCHEMBL11586470 0.80 ALDH1A1 (0.61) MAPTALDH1A1KMT2AMEN1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572351-B1 Bis-Schiff base compositions and formulations Systima Technologies, Inc. (US) 2023-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572351-B1 Bis-Schiff base compositions and formulations FHIT, H1-0, H1-2 MAPT 538/4885ALDH1A1 785/4885KMT2A 1738/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.