Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 12/20 | 0.62 |
| ▸ | MAPT | P10636 | 10/20 | 0.62 |
| ▸ | KMT2A | Q03164 | 10/20 | 0.62 |
| ▸ | MEN1 | O00255 | 9/20 | 0.62 |
| ▸ | GAA | P10253 | 6/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.62 |
| ▸ | ALOX12 | P18054 | 3/20 | 0.62 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.62 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ATM | Q13315 | 1/20 | 0.62 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.51 |
| ▸ | S100B | P04271 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | POLB | P06746 | 4/20 | 0.48 |
| ▸ | RECQL | P46063 | 3/20 | 0.48 |
| ▸ | BLM | P54132 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| N-Furfurylidene-P-Anisidine SCHEMBL11377145 | 1.00 | ALDH1A1 (0.62) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL14832002 | 0.83 | TDP1 (0.51) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL14832001 | 0.83 | TDP1 (0.51) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL7730775 | 0.81 | MAPT (0.52) | ALDH1A1MAPTKMT2AMEN1GAA | |
| N-Furfurylidene-P-Toluidine SCHEMBL24974694 | 0.81 | MAPT (0.68) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL23467270 | 0.80 | MAPT (0.54) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL17371004 | 0.79 | ALDH1A1 (0.69) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL3132675 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL21663529 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2AMEN1GAA | |
| SCHEMBL3132668 | 0.78 | ALDH1A1 (0.64) | ALDH1A1MAPTKMT2AMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0690856-B1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | UNIV NEW YORK STATE RES FOUND (US) | 2002-12-04 | — | — | EP | disclosed |
| US-5705508-A | FORMING TAXOL DERIVATIVES | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1998-01-06 | — | — | US | disclosed |
| US-5599820-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1997-02-04 | — | — | US | disclosed |
| EP-0690856-A4 | — | UNIV NEW YORK (US) | 1996-02-07 | — | — | EP | disclosed |
| EP-0690856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1996-01-10 | — | — | EP | disclosed |
| US-5475011-A | Anti-tumor compounds, pharmaceutical compositions, methods for preparation thereof and for treatment | THE RESEARCH FOUNDATION OF STATE UNIVERSITY OF NEW YORK (US) | 1995-12-12 | — | — | US | disclosed |
| WO-1994022856-A1 | ANTI-TUMOR COMPOUNDS, PHARMACEUTICAL COMPOSITIONS, METHODS FOR PREPARATION THEREOF AND FOR TREATMENT | THE RESEARCH FOUNDATION OF THE STATE UNIVERSITY OF NEW YORK (US) | 1994-10-13 | — | — | WO | disclosed |
| US-5294737-A | Hydrolysis, cyclization, condensation | THE RESEARCH FOUNDATION STATE UNIVERSITY OF NEW YORK (US) | 1994-03-15 | — | — | US | disclosed |
| US-4260743-A | Preparation of β-lactams and intermediates therefor | GIST-BROCADES N.V. (NL) | 1981-04-07 | — | — | US | disclosed |