SCHEMBL24974697

SCHEMBL24974697

CCc1cccc(/N=C/c2ccco2)c1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 8/20 0.50
ALDH1A1 P00352 7/20 0.50
MAPK1 P28482 4/20 0.50
MEN1 O00255 3/20 0.50
KMT2A Q03164 3/20 0.50
ALOX15 P16050 3/20 0.50
HSD17B10 Q99714 3/20 0.50
GAA P10253 2/20 0.50
L3MBTL1 Q9Y468 2/20 0.50
TSHR P16473 2/20 0.50
ESR2 Q92731 2/20 0.50
ALOX12 P18054 1/20 0.50
ATM Q13315 1/20 0.50
NPSR1 Q6W5P4 1/20 0.50
KDM4E B2RXH2 2/20 0.47
POLB P06746 3/20 0.43
APOBEC3A P31941 1/20 0.43
APOBEC3G Q9HC16 1/20 0.43
G6PC1 P35575 1/20 0.43
PIK3CA P42336 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24974695 0.83 MAPT (0.62) MAPTALDH1A1MAPK1MEN1KMT2A
N-Furfurylidene-M-Toluidine SCHEMBL24974696 0.80 ALDH1A1 (0.54) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL14832002 0.76 TDP1 (0.51) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL14832001 0.76 TDP1 (0.51) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL21663529 0.75 ALDH1A1 (0.64) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL3132675 0.75 ALDH1A1 (0.64) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL3132668 0.75 ALDH1A1 (0.64) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL14276992 0.74 KDM4E (0.45) MAPTALDH1A1MEN1KMT2AGAA
SCHEMBL23467260 0.74 MAPT (0.49) MAPTALDH1A1MAPK1MEN1KMT2A
SCHEMBL11818491 0.72 ALDH1A1 (0.61) MAPTALDH1A1MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11572351-B1 Bis-Schiff base compositions and formulations Systima Technologies, Inc. (US) 2023-02-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11572351-B1 Bis-Schiff base compositions and formulations FHIT, H1-0, H1-2 MAPT 538/4885ALDH1A1 785/4885MAPK1 3357/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.