Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.33 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.32 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 2/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 4/20 | 0.31 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428802 | 1.00 | HSD11B1 (0.33) | HSD11B1MAPK1GRM2NR1H2NR1H4 | |
| SCHEMBL24975437 | 0.97 | HSD11B1 (0.33) | HSD11B1MAPK1GRM2NR1H4PIK3CA | |
| SCHEMBL31429042 | 0.97 | HSD11B1 (0.33) | HSD11B1MAPK1GRM2NR1H4PIK3CA | |
| SCHEMBL31428683 | 0.91 | HSD11B1 (0.34) | HSD11B1MAPK1GRM2NR1H2NR1H4 | |
| SCHEMBL24975483 | 0.91 | HSD11B1 (0.34) | HSD11B1MAPK1GRM2NR1H2NR1H4 | |
| SCHEMBL24975466 | 0.88 | QRFPR (0.34) | HSD11B1MAPK1GRM2NR1H4PIK3CA | |
| SCHEMBL30163591 | 0.88 | QRFPR (0.34) | HSD11B1MAPK1GRM2NR1H4PIK3CA | |
| SCHEMBL31428527 | 0.87 | UCHL1 (0.38) | HSD11B1CREBBPBRD4 | |
| SCHEMBL24976131 | 0.85 | MAPK1 (0.31) | MAPK1 | |
| SCHEMBL24975829 | 0.84 | MAPK1 (0.32) | HSD11B1MAPK1NR1H4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |