Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.33 |
| ▸ | IGF1R | P08069 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | PLG | P00747 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | MTOR | P42345 | 1/20 | 0.32 |
| ▸ | CREBBP | Q92793 | 2/20 | 0.32 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.32 |
| ▸ | KIT | P10721 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | QRFPR | Q96P65 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24975483 | 1.00 | HSD11B1 (0.34) | HSD11B1MAPK1NR1H2IGF1RNR1H4 | |
| SCHEMBL24975466 | 0.97 | QRFPR (0.34) | HSD11B1MAPK1NR1H4GRM2PIK3CA | |
| SCHEMBL30163591 | 0.97 | QRFPR (0.34) | HSD11B1MAPK1NR1H4GRM2PIK3CA | |
| SCHEMBL24975440 | 0.91 | HSD11B1 (0.33) | HSD11B1MAPK1NR1H2NR1H4F10 | |
| SCHEMBL31428802 | 0.91 | HSD11B1 (0.33) | HSD11B1MAPK1NR1H2NR1H4F10 | |
| SCHEMBL24975437 | 0.88 | HSD11B1 (0.33) | HSD11B1MAPK1NR1H4GRM2PIK3CA | |
| SCHEMBL31429042 | 0.88 | HSD11B1 (0.33) | HSD11B1MAPK1NR1H4GRM2PIK3CA | |
| SCHEMBL31428476 | 0.87 | UCHL1 (0.39) | HSD11B1CREBBP | |
| SCHEMBL24977267 | 0.87 | UCHL1 (0.39) | HSD11B1CREBBP | |
| SCHEMBL31428517 | 0.83 | GRM2 (0.39) | HSD11B1NR1H4GRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | HSD11B1 3183/4885MAPK1 140/4885NR1H2 2120/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.