Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 2/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 7/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.34 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR2C | P28335 | 2/20 | 0.32 |
| ▸ | HTR2B | P41595 | 2/20 | 0.32 |
| ▸ | PDE11A | Q9HCR9 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24976603 | 0.84 | TGFBR1 (0.34) | SYKTGFBR1PTGS2PTGS1CHRNB2 | |
| SCHEMBL24976635 | 0.80 | SYK (0.36) | SYKPTGS2PTGS1 | |
| SCHEMBL24975374 | 0.79 | TRPV1 (0.37) | PDE4B | |
| SCHEMBL30469190 | 0.74 | TGFBR1 (0.38) | AAK1SYKTGFBR1PDE4B | |
| SCHEMBL25211504 | 0.74 | TGFBR1 (0.38) | AAK1SYKTGFBR1PDE4B | |
| SCHEMBL21492158 | 0.73 | CHRNB2 (0.55) | CHRNB2CHRNA4 | |
| SCHEMBL21492160 | 0.73 | CHRNB2 (0.55) | CHRNB2CHRNA4 | |
| SCHEMBL12958179 | 0.73 | MCHR1 (0.40) | AAK1TGFBR1PDE4B | |
| Hydrochloric Acid SCHEMBL21491545 | 0.72 | CHRNB2 (0.57) | CHRNB2CHRNA4 | |
| SCHEMBL20869211 | 0.69 | PDE4B (0.48) | TGFBR1PDE4BPTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023005894-A1 | INHIBITOR COMPOUND FOR WNT PATHWAY | 杭州阿诺生物医药科技有限公司 | 2023-02-02 | — | — | WO | disclosed |