Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 3/20 | 0.54 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | RAB9A | P51151 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.40 |
| ▸ | FABP1 | P07148 | 1/20 | 0.40 |
| ▸ | MMP1 | P03956 | 1/20 | 0.40 |
| ▸ | HTR5A | P47898 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428871 | 1.00 | MMP9 (0.54) | MMP9HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31428952 | 0.87 | MMP9 (0.49) | MMP9NPC1RAB9AKDM4EMAPT | |
| SCHEMBL24975797 | 0.87 | MMP9 (0.49) | MMP9NPC1RAB9AKDM4EMAPT | |
| SCHEMBL31428520 | 0.86 | MMP9 (0.48) | MMP9HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL31428958 | 0.83 | TDP1 (0.47) | NPC1RAB9AKDM4EGAATDP1 | |
| SCHEMBL24976051 | 0.83 | TDP1 (0.47) | NPC1RAB9AKDM4EGAATDP1 | |
| SCHEMBL24975622 | 0.82 | MAPK10 (0.49) | MMP9SLC40A1NPC1RAB9AKDM4E | |
| SCHEMBL31428882 | 0.82 | MAPK10 (0.49) | MMP9SLC40A1NPC1RAB9AKDM4E | |
| SCHEMBL24975610 | 0.82 | NPC1 (0.48) | NPC1RAB9AKDM4EGAATDP1 | |
| SCHEMBL31428836 | 0.82 | NPC1 (0.48) | NPC1RAB9AKDM4EGAATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |