Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.45 |
| ▸ | RAB9A | P51151 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428952 | 1.00 | MMP9 (0.49) | MMP9MAPTTP53ALDH1A1L3MBTL1 | |
| SCHEMBL31428871 | 0.87 | MMP9 (0.54) | MMP9MAPTNPC1RAB9AKDM4E | |
| SCHEMBL24975615 | 0.87 | MMP9 (0.54) | MMP9MAPTNPC1RAB9AKDM4E | |
| SCHEMBL31428520 | 0.86 | MMP9 (0.48) | MMP9MAPTTP53ALDH1A1L3MBTL1 | |
| SCHEMBL24975629 | 0.85 | ALDH1A1 (0.52) | MAPTTP53ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL31429002 | 0.85 | ALDH1A1 (0.52) | MAPTTP53ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL24975647 | 0.84 | MEN1 (0.53) | MAPTTP53ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL31428860 | 0.84 | MEN1 (0.53) | MAPTTP53ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL31428599 | 0.81 | NPC1 (0.55) | MAPTTP53ALDH1A1L3MBTL1NPC1 | |
| SCHEMBL9907526 | 0.80 | MAPT (0.52) | MAPTTP53ALDH1A1L3MBTL1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |