Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | HPGD | P15428 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | HTR5A | P47898 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 5/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 3/20 | 0.44 |
| ▸ | IP6K3 | Q96PC2 | 3/20 | 0.44 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24976051 | 1.00 | TDP1 (0.47) | TDP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL24975629 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL31429002 | 0.84 | ALDH1A1 (0.52) | ALDH1A1HPGDKDM4EMAPTNPC1 | |
| SCHEMBL31428871 | 0.83 | MMP9 (0.54) | TDP1KDM4EMAPTGAAHTR5A | |
| SCHEMBL24975615 | 0.83 | MMP9 (0.54) | TDP1KDM4EMAPTGAAHTR5A | |
| SCHEMBL31428992 | 0.81 | IP6K1 (0.53) | TDP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL31428983 | 0.80 | ALDH1A1 (0.49) | TDP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL24976050 | 0.80 | TDP1 (0.42) | TDP1ALDH1A1HPGDKDM4EMAPT | |
| SCHEMBL24976135 | 0.80 | TDP1 (0.42) | TDP1ALDH1A1HPGDMAPTHTR5A | |
| SCHEMBL24976053 | 0.80 | TDP1 (0.42) | TDP1ALDH1A1HPGDKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | NATIONAL UNIVERSITY CORPORATION KOBE UNIVERSITY (JP) | 2025-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250091994-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | BRAF, RAF1, NRAS | TDP1 3630/4885ALDH1A1 2352/4885HPGD 4233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.