Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428951 | 0.86 | HPGD (0.53) | KDM4EALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL24976108 | 0.77 | L3MBTL3 (0.40) | KDM2BHRH3KCNH2 | |
| SCHEMBL24976104 | 0.76 | KDM2B (0.41) | KDM4EKDM2BRAB9ANPC1HRH3 | |
| SCHEMBL25172234 | 0.74 | QDPR (0.44) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL31428621 | 0.70 | HPGD (0.49) | HPGDRAB9ANPC1HSD11B1CA12 | |
| SCHEMBL24975816 | 0.70 | HPGD (0.49) | HPGDRAB9ANPC1HSD11B1CA12 | |
| SCHEMBL31428431 | 0.68 | CAPN1 (0.55) | HPGDRAB9ANPC1HSD11B1CA12 | |
| SCHEMBL27297526 | 0.67 | NPC1 (0.70) | ALDH1A1MAPTHPGDHSD17B10RAB9A | |
| SCHEMBL29967134 | 0.67 | NAMPT (0.48) | KDM4EMAPTHTT | |
| SCHEMBL23410961 | 0.67 | NAMPT (0.48) | KDM4EMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |