Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 5/20 | 0.37 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | PIR | O00625 | 3/20 | 0.35 |
| ▸ | HSF1 | Q00613 | 2/20 | 0.35 |
| ▸ | BRAF | P15056 | 1/20 | 0.35 |
| ▸ | F10 | P00742 | 1/20 | 0.35 |
| ▸ | VNN1 | O95497 | 1/20 | 0.34 |
| ▸ | SPR | P35270 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31428637 | 0.86 | HPGD (0.47) | KDM2BCYP1A2SCN9AMEN1KMT2A | |
| SCHEMBL24975624 | 0.76 | KDM4E (0.41) | KDM2BKDM4ENPC1RAB9AKCNH2 | |
| SCHEMBL24976108 | 0.74 | L3MBTL3 (0.40) | KDM2BCYP1A2SCN9AKCNH2HRH3 | |
| SCHEMBL30163474 | 0.71 | KMT2A (0.56) | CYP1A2POLBKDM4ELMNACASP6 | |
| SCHEMBL31428645 | 0.68 | HPGD (0.57) | KDM4EKMT2AHRH3 | |
| SCHEMBL30163530 | 0.68 | SCN9A (0.54) | KDM2BSCN9AKCNH2 | |
| SCHEMBL31428690 | 0.68 | SCN9A (0.44) | SCN9APOLBLMNAMEN1KMT2A | |
| SCHEMBL31428689 | 0.68 | SCN9A (0.44) | SCN9APOLBLMNAMEN1KMT2A | |
| SCHEMBL999160 | 0.68 | TDP1 (0.58) | KDM2BCYP1A2POLBKDM4ELMNA | |
| SCHEMBL31201668 | 0.68 | NPC1 (0.55) | KDM2BCYP1A2POLBKDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023008577-A1 | RAS/RAF BINDING INHIBITOR COMPOUND | 国立大学法人神戸大学 | 2023-02-02 | — | — | WO | disclosed |