Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.30 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10551320 | 0.87 | TRPA1 (0.36) | GABRA1GABRB2 | |
| SCHEMBL10548882 | 0.85 | CASR (0.42) | CASRGABRA1GABRB2NR3C1NR3C2 | |
| SCHEMBL10553805 | 0.79 | CHRM3 (0.33) | CASR | |
| SCHEMBL20152370 | 0.76 | TRPA1 (0.35) | CASRGABRA1GABRB2 | |
| SCHEMBL31257140 | 0.76 | TRPA1 (0.35) | CASRGABRA1GABRB2 | |
| SCHEMBL31589377 | 0.73 | TSHR (0.47) | CASRL3MBTL1GABRA1GABRB2 | |
| SCHEMBL8785533 | 0.73 | TSHR (0.47) | CASRL3MBTL1GABRA1GABRB2 | |
| SCHEMBL11974108 | 0.72 | GABRA1 (0.33) | GABRA1GABRB2 | |
| SCHEMBL9641967 | 0.71 | CHRM3 (0.34) | CASR | |
| SCHEMBL2472104 | 0.70 | CASR (0.34) | CASRGABRA1GABRB2NR3C1NR3C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2370136-A1 | INHALATION DELIVERY METHODS AND DEVICES | MAP Pharmaceuticals Inc (US) | 2011-10-05 | — | — | EP | disclosed |
| US-20100196286-A1 | INHALATION DELIVERY METHODS AND DEVICES | MAP PHARMACEUTICALS, INC. | 2010-08-05 | — | — | US | disclosed |
| WO-2010065547-A1 | INHALATION DELIVERY METHODS AND DEVICES | MAP PHARMACEUTICALS, INC. (US) | 2010-06-10 | — | — | WO | disclosed |
| US-4826864-A | Substituted imidazole derivatives useful as antihypertensive or antithromtic agent or divretic | FARMOS GROUP LTD. (FI) | 1989-05-02 | — | — | US | disclosed |
| US-4639464-A | Antihypertensive substituted imidazole derivatives | FARMOS GROUP, LTD. (FI) | 1987-01-27 | — | — | US | disclosed |
| EP-0072615-B1 | SUBSTITUTED IMIDAZOLE DERIVATIVES AND THEIR PREPARATION AND USE | Farmos Group Ltd. (FI) | 1985-12-27 | — | — | EP | disclosed |
| US-4544664-A | Antihypertensive substituted imidazole derivatives | FARMOS GROUP, LTD. (FI) | 1985-10-01 | — | — | US | disclosed |
| EP-0072615-A1 | Substituted imidazole derivatives and their preparation and use | Farmos Group Ltd. (FI) | 1983-02-23 | — | — | EP | disclosed |